Shionogi & Co., Ltd.

Shionogi has aimed to fulfill its corporate mission of continually providing the superior medicines essential to people's health.

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baloxavir marboxilXofluza

cap-dependent endonuclease inhibitor

Baloxavir marboxil (Xofluza) is an oral antiviral used to treat acute uncomplicated influenza in patients 5 years of age and older and for post-exposure prophylaxis in that age group. It blocks the influenza virus's cap-snatching enzyme (PA endonuclease), stopping the virus from making the mRNA it needs to replicate. It is taken as a single oral dose for treatment.

Baloxavir marboxil is an antiviral medicine that treats and prevents the flu. It works by blocking an enzyme inside the flu virus called PA endonuclea

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