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Pfizer

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Pfizer is a global biopharmaceutical company committed to delivering breakthrough medicines that change patients' lives. The company maintains a global manufacturing network ensuring quality, scale, and delivery of medicines to patients worldwide. Pfizer's 2025 Impact Report highlights the company's ongoing commitment to innovation and patient access.

Source: https://www.pfizer.com/

atorvastatinLipitor
HMG-CoA reductase inhibitor (statin)

Lipitor (atorvastatin) is a statin that lowers LDL cholesterol by slowing its production in the liver and helping clear it from the blood. Beyond lowering numbers, it reduces the risk of heart attack and stroke in people with cardiovascular risk factors or established heart disease.

Most cholesterol in the blood is made by the liver. Atorvastatin blocks HMG-CoA reductase, the enzyme the liver needs to produce cholesterol. When the

azithromycinZithromax
macrolide antibacterial

Azithromycin (Zithromax) is an oral macrolide antibiotic used for mild to moderate infections caused by susceptible bacteria, including prophylaxis and treatment of disseminated Mycobacterium avium complex (MAC) disease in persons with advanced HIV infection. It works by binding to bacterial ribosomes and stopping production of proteins the bacteria need to grow and spread. It is not effective against viral infections.

Azithromycin is a macrolide antibiotic. It works by stopping bacteria from making the proteins they need to grow and multiply. It does this by attachi

celecoxibCelebrex
COX-2 selective nonsteroidal anti-inflammatory drug

Celecoxib (Celebrex) is an oral COX-2 selective nonsteroidal anti-inflammatory drug (NSAID) used for osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain, and primary dysmenorrhea. It blocks the COX-2 enzyme that makes pain-causing prostaglandins, while largely sparing the COX-1 enzyme that protects the stomach lining. It is taken by mouth in adults and children aged 2 years and older for certain indications.

Celecoxib belongs to a group of medicines called NSAIDs. It works by blocking an enzyme called COX-2. When tissues are injured or inflamed, COX-2 help

palbociclibIbrance
CDK4/6 inhibitor

Ibrance (palbociclib) is an oral CDK4/6 inhibitor from Pfizer for hormone receptor-positive, HER2-negative advanced or metastatic breast cancer. Combined with endocrine therapy, it blocks the cell-cycle machinery cancer cells use to multiply, slowing or stopping tumour growth.

Cancer cells multiply by cycling through growth and division, and many breast cancers lean heavily on the enzymes CDK4 and CDK6 to keep that cycle tur

pneumococcal 13-valent conjugate vaccinePrevnar 13
pneumococcal conjugate vaccine

Prevnar 13 is a conjugate vaccine that protects against disease caused by 13 serotypes of Streptococcus pneumoniae, including invasive pneumococcal disease, pneumonia, and otitis media. It is used in infants and children from six weeks of age and in adults 18 years and older.

Prevnar 13 contains capsular polysaccharides from 13 serotypes of Streptococcus pneumoniae, each chemically linked to a nontoxic diphtheria cross-reac

pregabalinLyrica
gabapentinoid anticonvulsant

Pregabalin (Lyrica) is an oral gabapentinoid used for neuropathic pain, adjunctive treatment of partial seizures, and generalised anxiety disorder in adults. It binds to calcium-channel subunits on overactive nerve cells, quieting the release of pain and excitatory signals. It is taken by mouth and is not a direct GABA agonist.

Pregabalin works by binding to specific subunits (called alpha-2-delta) on calcium channels at the ends of nerve cells in the brain and spinal cord. W

rimegepantNurtec ODT
CGRP receptor antagonist

Nurtec ODT (rimegepant) is a small-molecule CGRP receptor antagonist (a "gepant") from Pfizer. Taken as an orally disintegrating tablet, it both treats acute migraine attacks and, on an every-other-day schedule, prevents episodic migraine in adults.

Rimegepant is a tablet that blocks the receptor for calcitonin gene-related peptide (CGRP), a small protein released during migraine attacks. CGRP cau

sertralineZoloft
selective serotonin reuptake inhibitor

Zoloft (sertraline) is a selective serotonin reuptake inhibitor used for depression, obsessive-compulsive disorder, panic disorder, PTSD, social anxiety disorder, and premenstrual dysphoric disorder. It blocks the serotonin transporter, increasing serotonin signaling in mood and fear circuits. It is one of the most widely prescribed antidepressants.

Sertraline belongs to a group of antidepressants called selective serotonin reuptake inhibitors, or SSRIs. Nerve cells in the brain use a chemical cal

sildenafilViagra
PDE5 inhibitor

Viagra (sildenafil) is a PDE5 inhibitor originally from Pfizer. By blocking the enzyme that breaks down cGMP, it enhances blood flow to the penis during sexual stimulation, treating erectile dysfunction; a separate formulation (Revatio) treats pulmonary arterial hypertension.

Sildenafil belongs to a class called PDE5 inhibitors. During sexual stimulation, the body releases chemicals that relax the smooth muscle in the penis

tafamidisVyndaqel
transthyretin stabilizer (ATTR cardiomyopathy)

Vyndaqel and Vyndamax (tafamidis) are transthyretin stabilizers from Pfizer. In the United States they treat transthyretin amyloid cardiomyopathy to reduce cardiovascular death and hospitalization, and in the European Union tafamidis delays nerve damage in early hereditary transthyretin amyloid polyneuropathy.

Tafamidis belongs to the transthyretin stabilizer class. Transthyretin is a protein that can become unstable, break apart, and form amyloid deposits i

tofacitinibXeljanz
Janus kinase (JAK) inhibitor

Xeljanz (tofacitinib) is an oral Janus kinase inhibitor from Pfizer that calms overactive immune signalling. After TNF blockers have not worked, it treats rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, and certain childhood arthritis forms.

Tofacitinib is taken by mouth and belongs to the Janus kinase inhibitor class. It binds JAK enzymes and prevents activation of the JAK-STAT signalling