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Merck

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Merck is following the science to tackle some of the world's greatest health threats. The company works to improve lives through innovative medicines and vaccines.

Source: https://www.merck.com/

ezetimibeZetia
cholesterol absorption inhibitor

Ezetimibe (Zetia) is an oral medicine that lowers cholesterol by blocking its absorption in the small intestine. It is used alone or with other cholesterol-lowering medicines such as statins to reduce LDL ("bad") cholesterol in adults and children with inherited or acquired high cholesterol.

Ezetimibe works at the wall of the small intestine, where it blocks a transporter protein that normally absorbs cholesterol from food and bile. By red

human papillomavirus 9-valent vaccineGardasil 9
HPV vaccine

Gardasil 9 is Merck's nine-valent HPV vaccine. It presents virus-like particles from nine human papillomavirus types to the immune system, preventing the HPV infections that can cause cervical, anal and oropharyngeal cancers and genital warts.

Gardasil 9 contains virus-like particles made from the outer (L1) protein of nine HPV types. They are non-infectious - they are virus shells, not the

montelukastSingulair
leukotriene receptor antagonist

Montelukast (Singulair) is an oral medicine that blocks leukotrienes, inflammatory chemicals that tighten airways and trigger allergy symptoms. It is used for the prevention and long-term treatment of asthma, prevention of exercise-induced bronchoconstriction, and relief of seasonal and perennial allergic rhinitis.

Montelukast blocks a receptor called CysLT1 that is found on cells in the airways and throughout the body. When the body releases inflammatory chemica

pembrolizumabKeytruda
PD-1 checkpoint inhibitor

Keytruda (pembrolizumab) is a PD-1 checkpoint inhibitor from Merck used across many cancers, including melanoma, lung, kidney, gastric, and triple-negative breast cancers, Hodgkin lymphoma, and MSI-H or dMMR tumours. By releasing the PD-1 brake on T cells, it restores immune attack on cancer, alone or with combinations.

T cells are built to destroy abnormal cells, but many cancers protect themselves by displaying ligands PD-L1 and PD-L2 that bind the PD-1 off-switch o

sitagliptinJanuvia
DPP-4 inhibitor

Januvia (sitagliptin) is an oral DPP-4 inhibitor from Merck that improves blood sugar control in adults with type 2 diabetes. It is used alone or with metformin, a sulfonylurea, a thiazolidinedione, or insulin when diet and exercise are not enough.

Sitagliptin belongs to the DPP-4 inhibitor class. It blocks dipeptidyl peptidase-4, the enzyme that breaks down incretin hormones such as GLP-1. With